Question - Can Genvoya be crushed?

Answered by: Harold Campbell  |  Category: General  |  Last Updated: 27-06-2022  |  Views: 643  |  Total Questions: 5

“Do not crush” antiretroviral drugs Unfortunately, there are no alternative formulations available for Genvoya and many other STRs. Whether a pill can be crushed, split, or opened depends on its components and formulation. Crushing or splitting Genvoya has not been studied, thus it is not recommended. Oral Solution or Powder or Other Elvitegravir + Cobicistat + Emtricitabine + Tenofovir alafenamide Genvoya Tablets should not be chewed, crushed, or split. Crushing of tablets is not recommended in the product information. TENOFOVIR 300mg tablet Tablets may be split or chewed (bitter taste) May dissolve crushed tablet in 100 mL water, grape juice or grapefruit juice & take within 20 min. May split tab and insert in empty gelatin capsule to mask bitter taste. May have bitter taste. Tablets can be crushed and added to small amount of liquid or semi-solid food; consume immediately. Crushing or splitting Descovy® tablets has not been studied and is not recommended. TAF is soluble in water. Crushing of dolutegravir fixed-dose combination tablets increases dolutegravir exposure. Currently, there is no information about crushing of the branded fixed-dose combination of dolutegravir/abacavir/lamivudine (Triumeq®, referred to as TRI); therefore, crushing of TRI is not recommended.

https://www.healthline.com/health/lamivudine-oral-tablet

General. You can take lamivudine with or without food. You can cut or crush the lamivudine tablet. If you have trouble using the tablet form of the drug, ask your doctor about the solution form.

https://www.genvoya.com/hcp

GENVOYA® tablets By following this link, you are now leaving www. STRIBILD. com. This site is not controlled by Gilead Sciences, Inc. Gilead Sciences, Inc. is not responsible for the site's content or your use of it.

https://www.businessinsider.com/fda-approves-gsk-next-generation-hiv-drug-dolutegravir-2017-11

The pill, which contains dolutegravir with rilpivirine, is made by ViiV, the specialist HIV company majority owned by GlaxoSmithKline, that has Pfizer and Japanese pharmaceutical company Shionogi as shareholders.

https://www.rxlist.com/descovy-side-effects-drug-center.htm

Descovy (emtricitabine and tenofovir alafenamide) is a two-drug combination of two HIV nucleoside analog reverse transcriptase inhibitors (NRTIs), and is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 12 years of age and older.

https://www.drugs.com/descovy.html

Emtricitabine and tenofovir alafenamide are antiviral medicines that prevent human immunodeficiency virus (HIV) from multiplying in your body. Descovy is a presciption medicine used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS).