Miscarriage can occur in any pregnancy. It is not known if taking ziprasidone would increase this chance for miscarriage. There are no well controlled studies on ziprasidone use during pregnancy in humans. This drug should not be used during pregnancy unless the benefit outweighs the risk to the fetus. Comments: Neonates exposed to antipsychotic drugs during the third trimester of pregnancy are at risk for extrapyramidal and /or withdrawal symptoms following delivery. As a result, there is an increase in the number of women requiring antipsychotic drug therapy who are likely to become pregnant. To date, no definitive association has been found between use of antipsychotics during pregnancy and an increased risk of birth defects or other adverse outcomes. As many as 1 in 5 pregnancies end in miscarriage even when a woman has not taken any medication. The evidence we have suggests that antipsychotics do not increase the risk of miscarriage3 – but we need more research to be sure about this. Miscarriage can occur in any pregnancy. One study reported an increased chance of miscarriage in women taking antipsychotic medications (including quetiapine) during pregnancy when compared with groups that were not taking such medications.
Category B drugs include prenatal vitamins, acetaminophen and several other medications used routinely and safely during pregnancy. If there is a clinical need for a Category B drug, it is considered safe to use it. Drugs should be given only if the potential benefit justifies the potential risk to the fetus. "
If you are taking this medication to help with symptoms of mood disturbance, you may notice some changes in the first 1 to 2 weeks. Medications like ziprasidone do not work for everyone. If you are not feeling better within 6 weeks, your doctor may recommend switching you to a different medication.
Safety of Psychiatric Medications During Pregnancy and Lactation Drug FDA pregnancy category* Chlorpromazine (Thorazine)‡ C Clozapine (Clozaril) B Fluphenazine (Prolixin)‡ C Haloperidol (Haldol) C
Category C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
While benzodiazepines are category D, long-term anxiety medications like Prozac and Zoloft are often described as “probably safe. ” Tricyclic antidepressants and buspirone may be safe during pregnancy as well.
Treatment Options for Women With Bipolar Disorder During Pregnancy Lithium; Antiepileptic medications including carbamazepine, lamotrigine, and valproic acid; and. Atypical antipsychotic medications: aripiprazole, olanzapine, quetiapine, risperidone, and ziprasidone.
Generally, these antidepressants are an option during pregnancy: Certain selective serotonin reuptake inhibitors (SSRIs). SSRIs are generally considered an option during pregnancy, including citalopram (Celexa) and sertraline (Zoloft). Potential complications include maternal weight changes and premature birth.
Side Effects. Drowsiness, dizziness, lightheadedness, weakness, nausea, vomiting, runny nose, and cough may occur. If any of these effects persist or worsen, tell your doctor promptly. Dizziness and lightheadedness can increase the risk of falling.
While all drugs pass through the placenta, quetiapine shows the lowest degree of placenta transit of all the antipsychotics. Studies with animals have not showed any teratogenic effect.
Antipsychotics shown safe for pregnant women and their babies. The use of antipsychotic drugs during pregnancy has increased considerably over the years, as more women with serious psychiatric conditions, such as schizophrenia and bipolar disorder, go on to have successful pregnancies, Dr. Vigod says.
Use of quetiapine during pregnancy is a common concern for women experiencing schizophrenia who want to maintain mental health without jeopardizing the health and wellness of their developing baby. However, there is not enough data on the safety of quetiapine, more commonly called Seroquel, during pregnancy.
Quetiapine is an antipsychotic • Low folate is not good for a healthy pregnancy and can cause spine problems in the baby • Taking folic acid daily before and during pregnancy can help reduce the risk of your baby having spine problems.
The atypical antipsychotics (AAP; also known as second generation antipsychotics (SGAs)) are a group of antipsychotic drugs (antipsychotic drugs in general are also known as major tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s
A total of around 3, 000 pregnant women taking olanzapine have been studied. There is currently no suggestion of any link between olanzapine use in pregnancy and general birth defects in the baby.