Question - Can omeprazole affect pregnancy?

Answered by: Ronald Young  |  Category: General  |  Last Updated: 24-06-2022  |  Views: 952  |  Total Questions: 14

Omeprazole is widely used in pregnant women. It is not known to be harmful to an unborn baby, but as is the case for nearly all medicines, the possible effects that exposure in the womb may have on a child's longer term health have not been studied. Usually, omeprazole is safe to take during pregnancy and while breastfeeding. If you're pregnant, it's always better to try to treat indigestion without taking a medicine. Your doctor or midwife will first advise that you try to ease your symptoms by eating smaller meals more often and avoiding fatty and spicy foods. Omeprazole side effects Adult side effects can include: headache. stomach pain. nausea. diarrhea. vomiting. gas. Children's side effects can include the above, plus the following: fever. If you are taking Prilosec and find out that you are pregnant, you should consult your doctor immediately. Dr. Roshan advises his pregnant patients against taking Prilosec in the first trimester, since it is classed as a category C, but Dr. Roshan says women can take it in the second and third trimesters, if necessary. Over-the-counter antacids such as Tums, Rolaids, and Maalox may help you cope with occasional heartburn symptoms. Those made of calcium carbonate or magnesium are good options. However, it may be best to avoid magnesium during the last trimester of pregnancy.

https://www.ncbi.nlm.nih.gov/pubmed/9757979

CONCLUSIONS: No association was found between exposure to omeprazole during the period of organogenesis and increased risk for major malformations. Exposure throughout pregnancy is not associated with increased risk of spontaneous abortions, decreased birth weight, or perinatal complications.

https://www.drugs.com/uk/omeprazole-20mg-capsules-leaflet.html

If you notice any of the following rare but serious side effects, stop taking omeprazole 20 mg capsules and contact a doctor immediately: Sudden wheezing, swelling of your lips, tongue and throat or body, rash, fainting or difficulties in swallowing (severe allergic reaction).

https://www.goodrx.com/omeprazole/what-is

Omeprazole is used to treat certain conditions where there is too much acid in the stomach. It is used to treat gastric and duodenal ulcers, erosive esophagitis, and gastroesophageal reflux disease (GERD). GERD is a condition where the acid in the stomach washes back up into the esophagus.

https://www.glowm.com/resources/glowm/cd/pages/resources/Pharmacy/Pregnancy_Categories.htm

Category B drugs include prenatal vitamins, acetaminophen and several other medications used routinely and safely during pregnancy. If there is a clinical need for a Category B drug, it is considered safe to use it. Drugs should be given only if the potential benefit justifies the potential risk to the fetus. "

https://www.mayoclinic.org/drugs-supplements/omeprazole-oral-route/proper-use/drg-20066836

Adults—20 milligrams (mg) once a day before a meal. Your doctor may want you to take omeprazole for more than 8 weeks for certain conditions. Children 1 year of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 to 20 mg once a day before a meal.

https://americanpregnancy.org/is-it-safe/tums-during-pregnancy/

TUMS provides safe heartburn relief for women who are pregnant. TUMS also adds calcium to your body. When you are pregnant, your body may need between 1, 000 mg and 1, 300 mg of elemental calcium per day. Be sure to take TUMS at a different time than you take iron supplements.

https://www.healthline.com/health/heartburn/zantac-during-pregnancy

Zantac is considered safe to take at any time during pregnancy. OTC drugs do not have pregnancy categories, but prescription Zantac is considered a pregnancy category B drug by the U. S. Food and Drug Administration (FDA). Category B means that studies have shown Zantac is not harmful to a developing fetus.

https://www.nhs.uk/common-health-questions/pregnancy/can-i-take-paracetamol-when-i-am-pregnant/

Paracetamol has been used routinely during all stages of pregnancy to reduce a high temperature and for pain relief. There's no clear evidence it has any harmful effects on an unborn baby. But as with any medicine taken during pregnancy, use paracetamol at the lowest effective dose for the shortest possible time.

https://www.medsafe.govt.nz/Profs/Datasheet/p/panadolextraadvancetab.pdf

Pregnancy Category A – Both Paracetamol and Caffeine have been taken by a large number of pregnant women and women of childbearing age without any proven increase in the frequency of malformations.

https://www.health.com/condition/heartburn/12-ways-to-soothe-heartburn-in-pregnancy

Heartburn plagues most moms-to-be at some point because progesterone, the hormone that relaxes muscles in pregnancy, also relaxes the stomach valve that keeps acid out of the esophagus. In addition, the growing uterus crowds the stomach, forcing acid into the esophagus.

https://mothertobaby.org/fact-sheets/proton-pump-inhibitors/

Omprezole is the best studied of the proton pump inhibitors. Multiple studies including over 6, 610 women exposed to omeprazole, 1, 630 exposed to lansoprazole, 560 exposed to pantoprazole, 700 exposed to esomeprazole, and 44 exposed to rabeprazole have shown no increase in the chance of birth defects.

https://www.aafp.org/afp/2003/0615/p2517.html

Use of OTC Pain Medications in Pregnancy Drug name FDA pregnancy risk classification by trimester (1st/2nd/3rd) Drug class Aspirin D/D/D Salicylate analgesic/antipyretic Ibuprofen (Advil, Motrin) B/B/D NSAID analgesic Ketoprofen (Orudis) B/B/D NSAID analgesic Naproxen (Aleve) B/B/D NSAID analgesic

https://www.drugwatch.com/proton-pump-inhibitors/alternatives/

These include proton pump inhibitors such as esomeprazole (Nexium), omeprazole (Prilosec), pantoprazole (Protonix) and lansoprazole (Prevacid). The others are antacids such as Maalox, Mylanta and Tums; and H2 (histamine) receptor antagonists such as ranitidine (Zantac), famotidine (Pepcid), and cimetidine (Tagamet).