Question - Can omeprazole be given IM?

Answered by: Susan Jackson  |  Category: General  |  Last Updated: 24-06-2022  |  Views: 1180  |  Total Questions: 14

In the present study, omeprazole was administered i. m. On average, both doses of omeprazole (0. 25 or 1. 0 mgkg bwt) significantly inhibited the stimulated acid output during the observation period with 64 and 97%, respectively, in comparison with controls. In patients with Zollinger-Ellison Syndrome the recommended initial dose of Omeprazole given intravenously is 60 mg daily. When doses exceed 60 mg daily, the dose should be divided and given twice daily. Omeprazole is to be administered in an intravenous infusion for 20-30 minutes. Omeprazole Injection 40 mg is indicated primarily for the treatment of Zollinger-Ellison syndrome, and may also be used for the treatment of gastric ulcer, duodenal ulcer and reflux oesophagitis. Ask your doctor if you have any questions. Take omeprazole capsules or delayed-release capsules before a meal, preferably in the morning. Omeprazole tablets may be taken with food or on an empty stomach. Take omeprazole powder for oral suspension on an empty stomach at least 1 hour before a meal. Initially 80mg IV; given as 40mg omeprazole in 100ml sodium chloride 0. 9% infused over 20 – 30 minutes, then repeat. Followed by IV continuous infusion of 8mg/hr for 72 hours. (1) Given as 40mg omeprazole in 100ml sodium chloride 0. 9% or 5% dextrose; infuse at 20ml (8mg) per hour over 5 hours for a total of 72 hours.

https://prilosecotc.com/en-us/article/faqs-about-prilosec-otc

Prilosec OTC starts to work on the very first day of treatment, but may take 1 to 4 days for full effect (although some people get complete relief within 24 hours). Even though you may feel heartburn relief in the first few days, make sure to take the entire 14 days of dosing to treat your frequent heartburn.

https://www.healthline.com/health/omeprazole-oral-capsule-sprinkles

Omeprazole side effects Adult side effects can include: headache. stomach pain. nausea. diarrhea. vomiting. gas. Children's side effects can include the above, plus the following: fever.

https://www.mayoclinic.org/diseases-conditions/gastritis/diagnosis-treatment/drc-20355813

Medications that block acid production and promote healing. These drugs include the prescription and over-the-counter medications omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), esomeprazole (Nexium), dexlansoprazole (Dexilant) and pantoprazole (Protonix).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002568/

Currently, three IV PPIs are available in the US (esomeprazole, pantoprazole and lanzoprazole). IV omeprazole is available in Europe and Asia.

https://www.rxlist.com/consumer_omeprazole_prilosec/drugs-condition.htm

Common side effects of omeprazole include: headache. abdominal pain. diarrhea. nausea. vomiting. gas (flatulence) dizziness. upper respiratory infection.

https://prilosecotc.com/en-us/article/heartburn-diet-and-tips

Heartburn foods to avoid: Foods that are fried, sautéed, or prepared in butter or oil. High-fat side dishes such as onion rings or French fries. High-fat sauces, gravies, and salad dressings. Tomato-based foods and juices. Caffeinated beverages such as cola and iced tea. Citrus drinks such as lemonade or orange juice.

https://www.nhs.uk/medicines/omeprazole/

Omeprazole also comes as a tablet that melts in your mouth. You can buy omeprazole 10mg tablets and capsules from pharmacies. They're the same as omeprazole 10mg tablets and capsules that you get on prescription, but they're meant to be taken only by adults, and only for up to 4 weeks.

https://www.rxlist.com/prilosec-drug.htm

Dosage Forms And Strengths PRILOSEC For Delayed-Release Oral Suspension, 2. 5 mg or 10 mg, is supplied as a unit dose packet containing a fine yellow powder, consisting of white to brownish omeprazole granules and pale yellow inactive granules.

https://www.drugwatch.com/proton-pump-inhibitors/alternatives/

These include proton pump inhibitors such as esomeprazole (Nexium), omeprazole (Prilosec), pantoprazole (Protonix) and lansoprazole (Prevacid). The others are antacids such as Maalox, Mylanta and Tums; and H2 (histamine) receptor antagonists such as ranitidine (Zantac), famotidine (Pepcid), and cimetidine (Tagamet).

https://www.everydayhealth.com/drugs/prilosec

Prilosec Interactions Certain antibiotics, such as ampicillin (Principen, Unasyn) Anticoagulants (often called "blood thinners") such as warfarin (Coumadin, Jantoven), rivaroxaban (Xarelto), and apixaban (Eliquis). Atazanavir (Reyataz) Benzodiazepines such as diazepam (Valium) Cilostazol (Pletal) Clopidogrel (Plavix)

https://www.practiceupdate.com/content/my-approach-to-tapering-off-a-proton-pump-inhibitor/36802

Before the quit date: Taper down the dose. For example, if someone is on 20 mg of omeprazole twice daily, I will reduce the dose to 20 mg a day for 10 days and then 20 mg every other day for 10 days before stopping. Address emotional stress. Extreme stress can cause vomiting. Improve nutrition.

https://www.drugs.com/uk/omeprazole-20mg-capsules-leaflet.html

Omeprazole 20 mg capsules is used to treat the following conditions: In adults: 'Gastro-esophageal reflux disease' (GERD). This is where acid from the stomach escapes into the gullet (the tube which connects your throat to your stomach) causing pain, inflammation and heartburn.

https://www.goodrx.com/omeprazole/what-is

Omeprazole is used to treat certain conditions where there is too much acid in the stomach. It is used to treat gastric and duodenal ulcers, erosive esophagitis, and gastroesophageal reflux disease (GERD). GERD is a condition where the acid in the stomach washes back up into the esophagus.

https://www.webmd.com/heartburn-gerd/guide/prescription-treatments

They include: Rabeprazole (Aciphex) Esomeprazole (Nexium) Lansoprazole (Prevacid) Omeprazole (Prilosec, Zegerid) Pantoprazole (Protonix) Dexlansoprazole (Dexilant)