Question - Is Laryngopharyngeal reflux serious?

Answered by: Randy Ward  |  Category: General  |  Last Updated: 23-06-2022  |  Views: 1206  |  Total Questions: 14

Complications of LPR Stomach acid that pools in the throat and larynx can cause long-term irritation and damage. Without treatment, it can be serious. In infants and children, LPR can cause: Narrowing of the area below the vocal cords. Some people recover completely for months or years and then may have a relapse. In one way, having LPR is a little like having high blood pressure – with treatment, LPR does not usually cause serious medical problems, but without treatment, LPR can be serious, even dangerous. Follow a bland diet (low acid levels, low in fat, not spicy). Eat frequent, small meals. Lose weight. Avoid the use of alcohol, tobacco and caffeine. Do not eat food less than 2 hours before bedtime. Raise the head of your bed before sleeping. Avoid clearing your throat. You have been diagnosed with laryngopharyngeal reflux, or LPR. This condition is due to a small amount of stomach acid and enzymes making their way into your larynx, or voice box. While LPR is not a dangerous condition, there have been reported cases of patients developing cancer from chronic reflux. In contrast to GERD, the therapeutic response of patients with LPR to PPIs is variable, 22 in part because LPR requires more aggressive and prolonged therapy than GERD. Although most patients show improvement of symptoms within 3 months, the resolution of symptoms and laryngeal findings generally takes 6 months.

https://med.stanford.edu/content/dam/sm/ohns/documents/voicecenter/resources/Stanford_ENT_Clinic-LPR

Proton Pump Inhibitors (PPIs) are the most effective medicines for the treatment of LPR. Remember that LPR is different from GERD and its successful treatment requires higher doses of medicine for a prolonged period of time.

https://www.racgp.org.au/afp/2017/januaryfebruary/laryngopharyngeal-reflux-a-confounding-cause-of-ae

Prevalence. Half of the laryngeal complaints referred to ear, nose and throat (ENT) services are ultimately diagnosed as LPR. Meta-analysis of pH studies reveals reflux in 63% of patients with LPR, compared with 30% in controls, 2 and reflux is seven times more frequent in this group.

https://www.uspharmacist.com/article/laryngopharyngeal-reflux-silent-reflux

LPR differs from gastroesophageal reflux disease (GERD) in that it is frequently not associated with heartburn and regurgitation. Fewer than 50% of patients with laryngeal acid exposure have typical symptoms of heartburn and regurgitation; thus, the term silent reflux has been used to refer to LPR.

http://www.jcmrp.eg.net/article.asp?issn=2357-0121;year=2017;volume=2;issue=1;spage=67;epage=72;aula

There is a strong association between psychological symptoms and the presence of LPR; the most commonly detected manifestation was anxiety, and there was a positive significant correlation with anxiety and a negative significant correlation between depression and reflux symptoms.

https://www.refluxgate.com/ultimate-guide-to-lpr-causes-and-treatment

The Fundoplication is proven to work for most LPR patients. However, side effects like bloating are common and can be severe. Also, it is a permanent option. You can redo it if the wrap loosens up.

https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-lifestyle-changes-may-ease-laryngo

Foods that people with laryngopharyngeal reflux should avoid include spicy, fried and fatty foods; citrus fruits; tomatoes; chocolate; peppermint; cheese; and garlic. Foods that contain caffeine, carbonated beverages and alcohol also can worsen symptoms.

https://www.refluxgate.com/apple-cider-vinegar

Apple cider vinegar makes LPR symptoms worse. Apple cider vinegar is acidic, which means that it has a low pH. Foods with a low pH are problematic for people with silent reflux/LPR. As long as pepsin is inside the stomach, promoting its activity by lowering the pH might stimulate digestion.

https://my.clevelandclinic.org/health/diseases/15024-laryngopharyngeal-reflux-lpr

What causes laryngopharyngeal reflux? LPR is caused by stomach acid that bubbles up into the throat. When you swallow, food passes down your throat and through your esophagus to your stomach. A muscle called the lower esophageal sphincter controls the opening between the esophagus and the stomach.

https://www.sciencedaily.com/releases/2009/10/091026152940.htm

Overall survival at 10 years after diagnosis was 68 percent. Causes of death included 28 percent from cardiovascular disease, 7 percent from dementia and 7 percent from esophageal cancer.

https://www.hopkinsmedicine.org/otolaryngology/specialty_areas/voice_center/conditions/chronic_cough

A cough is considered chronic when it lasts for eight weeks or longer. It's important to evaluate and manage all possible causes of persistent coughing. Chronic cough is often caused by laryngopharyngeal reflux, commonly known as LPR.

https://www.massgeneral.org/digestive/treatments-and-services/barretts/faq

Individuals with chronic GERD symptoms (typically more than five years), and particularly those with significant risk factors, should undergo screening for Barrett's esophagus with endoscopy every three to five years.

https://www.bmc.org/otolaryngology/conditions-we-treat/throat/laryngopharyngeal-reflux-lpr

What role does an ear, nose, and throat specialist have in treating GERD and LPR? A gastroenterologist, a specialist in treating gastrointestinal orders, will often provide initial treatment for GERD.

https://www.healthline.com/health/barretts-esophagus

Recognizing the symptoms of Barrett's esophagus Barrett's esophagus does not have any symptoms. However, because most people with this condition also have GERD, they will usually experience frequent heartburn. Call your doctor right away if any of the following symptoms occur: having chest pain.

https://www.roswellpark.org/cancertalk/201804/esophageal-cancer-qa-dr-fountzilas

4. How long does it take for Barrett's esophagus to develop into cancer? Barrett's esophagus increases your risk of developing adenocarcinoma, the most common type of esophageal cancer. But if Barrett's esophagus does turn into cancer, it is a slow process that takes several years.