Question - What drugs can cause Livedo Reticularis?

Answered by: Terry Campbell  |  Category: General  |  Last Updated: 16-06-2022  |  Views: 1063  |  Total Questions: 13

Causes Adderall (side effect) Amantadine (side effect) Bromocriptine (side effect) Beta interferon treatment, e. g. in multiple sclerosis. Livedo reticularis associated with rasagiline. Methylphenidate and dextroamphetamine-induced peripheral vasculopathy. Gefitinib. There is no specific treatment for livedo reticularis, except for cold avoidance. In some patients, the symptoms may improve spontaneously with age. Rewarming the area in idiopathic cases or treatment of the underlying cause of secondary livedo may reverse the discolouration. Livedo reticularis: A mottled purplish discoloration of the skin. Livedo reticularis has been reported in association with autoimmune diseases, such as systemic lupus erythematosus; abnormal antibodies referred to as phospholipid antibodies; and a syndrome featuring phospholipid antibodies with multiple brain strokes. Livedo reticularis is a rare skin condition caused by stagnation of blood within dilated capillaries causing a lacy, nonraised pink/purple net-like blotchy skin discoloration. In itself it is not dangerous, but the etiology should be determined as many causes are potentially dangerous. The Antiphospholipid Syndrome Livedo reticularis is relatively common, occurring in 24% of a series of 1000 aPL patients (Fig. 141. 4). Livedo reticularis is usually widespread and can localize on nonadjacent areas on the limbs, trunk, and buttocks.

https://www.dermcoll.edu.au/atoz/livedo-reticularis/

Generally, livedo reticularis arises from altered blood flow in the skin microcirculation (the small blood vessels that supply the skin). However, in physiologic livedo reticularis, the pattern tends to disappear when the affected area is warmed.

https://www.pennmedicine.org/updates/blogs/health-and-wellness/2017/december/raynauds

You don't need to have a disease to get secondary Raynaud's. Certain blood pressure, migraine, cancer medications, birth control pills, and over-the-counter cold medications, can all be the culprit. Smokers also have an increased risk of Raynaud's —As well as heart attack, stroke, and lung cancer.

https://www.medicalnewstoday.com/articles/322371

Symptoms of poor circulation Numbness and tingling in extremities. One of the most common symptoms of poor circulation is numbness and tingling in the hands and feet. Cold hands and feet. Swelling in the lower extremities. Cognitive dysfunction. Digestive problems. Fatigue. Joint pain and muscle cramping. Skin color changes.

https://www.medicalnewstoday.com/articles/321422.php

Mottled skin is not harmful in and of itself. However, it may indicate an underlying condition. The outlook for each condition that may cause mottled skin is different. As a general rule, the sooner a doctor diagnoses the condition, the better it can be treated or managed.

https://www.mayoclinic.org/livedo-reticularis/expert-answers/faq-20057864

Livedo reticularis is thought to be due to spasms of the blood vessels or an abnormality of the circulation near the skin surface. It makes the skin, usually on the legs, look mottled and purplish, in sort of a netlike pattern with distinct borders. Sometimes livedo reticularis is simply the result of being chilled.

https://rarediseases.info.nih.gov/diseases/7664/sneddon-syndrome

Sneddon syndrome is a rare, progressive condition that affects blood vessels. It is primarily characterized by livedo reticularis (net-like patterns of discoloration on the skin) and neurological abnormalities. The cause of Sneddon syndrome is often unknown, but it is sometimes associated with an autoimmune disease.

https://www.webmd.com/dvt/ss/slideshow-dvt-improve-circulation

Signs of Poor Circulation When your limbs can't get enough blood, your hands or feet may feel cold or numb. If you're light-skinned, your legs might get a blue tinge. Poor circulation also can dry your skin, turn your nails brittle, and make your hair fall out, especially on your feet and legs.

https://www.crossroadshospice.com/hospice-caregiver-support/end-of-life-signs/mottled-skin-before-de

Mottling is caused by the heart no longer being able to pump blood effectively. Because of this, blood pressure drops, causing extremities to feel cool to the touch. The skin then starts to become discolored.

https://www.healthline.com/health/mottled-skin

Drugs that are known to cause mottled skin include: amantadine. catecholamines. minocycline (Minocin) gemcitabine (Gemzar)

https://emedicine.medscape.com/article/1082675-overview

Livedoid vasculopathy (LV), or livedoid vasculitis, is a hyalinizing vascular disease characterized by thrombosis and ulceration of the lower extremities. Atrophie blanche in livedoid vasculopathy.

https://www.nidirect.gov.uk/conditions/dehydration

Signs of severe dehydration in a child include: decreased level of consciousness. pale or mottled skin.

https://www.footsmart.com/pages/leg-circulation

Poor circulation is often a sign of other health issues, such as obesity, high blood pressure or cholesterol, and diabetes. Another common cause of poor circulation is peripheral vascular disease (PVD), a condition that restricts normal blood flow to and from the heart.

https://www.lupus.org/resources/how-lupus-is-diagnosed-an-overview

There is no single diagnostic test for systemic lupus. The test you will hear most about is called the antinuclear antibody (ANA) test. This is not a specific test for lupus, however. In fact, a variety of laboratory tests are used to detect physical changes or conditions in your body that can occur with lupus.