Question - When was Lexapro invented?

Answered by: Douglas James  |  Category: General  |  Last Updated: 20-06-2022  |  Views: 524  |  Total Questions: 14

Lexapro has been commercially available in the US since its original launch in 2002, and has been prescribed to more than 18 million US adults for depression, anxiety or both. Forest licensed Lexapro from the Danish pharmaceutical company, Lundbeck when the drug was in the clinical stage. Although fluoxetine was the first SSRI approved and marketed in the United States, the clinical trials (Phase I-Phase III) lasted more than seven years and during that time Astra AB introduced the first SSRI zimeldine (Zelmid®) to the European market in March 1982. Escitalopram was approved in 2002, and it has been manufactured and marketed by U. S. -based Forest Laboratories Inc., in partnership with the Danish drug company Lundbeck. While medications with a short half-life can leave a person's body within two days, medications with a longer half-life can take up to four weeks to leave a person's body. Lexapro's half-life is 27 to 32 hours.

https://www.goodtherapy.org/blog/major-depression-eased-with-high-doses-of-lexapro-111312

At regular intervals, Lexapro dosage was increased up to a maximum of 50 mg or until remission of symptoms. Thirty-eight percent of those required a dosage of 50 mg. At doses higher than 40 mg, side effects became more pronounced although not necessarily more severe.

https://www.addictionhope.com/lexapro/

The FDA has determined that Lexapro is not addictive or habit-forming. However, if someone abusing Lexapro abruptly stops taking escitalopram, they will endure physical withdrawal symptoms. In addition to the physical withdrawal effects, they will experience negative psychological reactions as well.

https://www.webmd.com/depression/news/20020815/new-antidepressant-approved

New Antidepressant Approved. Aug. Celexa and Lexapro are both part of the new generation of prescription antidepressant drugs known as SSRIs (selective serotonin reuptake inhibitors), which also includes Prozac, Zoloft, and Paxil.

https://deserthopetreatment.com/antidepressants/escitalopram-lexapro-addiction/

Is Escitalopram Addictive? This medication is not considered addictive, although some people develop a tolerance to it, and dependence on it, which can lead to withdrawal symptoms.

https://www.everydayhealth.com/drugs/lexapro

Lexapro is safe for adults and for adolescents/teens 12 to 17 years old. Children younger than 12 should not take Lexapro.

https://www.medicalnewstoday.com/articles/322444.php

Lexapro is safe to take over an extended period. Many experts believe that this type of medication is less likely than older antidepressants to cause weight gain. Older forms of antidepressant medication include monoamine oxidase inhibitors and tricyclic antidepressants.

https://www.goodrx.com/lexapro/what-is

Lexapro (escitalopram) is good for treating depression and anxiety. It is less likely to cause side effects and has fewer drug interactions than other antidepressants.

https://www.verywellmind.com/lexapro-withdrawal-symptoms-timeline-and-treatment-4707910

Lexapro withdrawal symptoms typically arrive one to three days after your last dose. There are, however, cases where it started sooner (within hours) or later (more than a week). Symptoms generally resolve within a few weeks, although they can potentially continue longer.

https://www.drugaddictiontreatment.com/types-of-addiction/prescription-drug-addiction/lexapro-addict

Even though it can cause a withdrawal syndrome, the United States government does not classify Lexapro and other SSRIs as controlled, addictive substances. Lexapro is sold as 10mg film-coated white oval pills with the letters E and L on one side, or as 20mg white oval pills with the letters E and N on one side.

https://www.medicinenet.com/lexapro_vs_xanax/article.htm

Lexapro is a selective serotonin reuptake inhibitor (SSRI) and Xanax is a benzodiazepine. Side effects of Lexapro and Xanax that are similar include drowsiness and weight changes.

https://www.drugs.com/price-guide/lexapro

The cost for Lexapro oral tablet 5 mg is around $1, 212 for a supply of 100 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. A generic version of Lexapro is available, see escitalopram prices.

https://www.medicinenet.com/beta-blockers_vs_ssris/article.htm

One similarity is that some beta-blockers and some SSRIs may be used to treat anxiety. Examples of SSRIs include citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox, Luvox CR), paroxetine (Paxil, Paxil CR, Pexeva), sertraline (Zoloft), and vilazodone (Viibryd).

https://www.webmd.com/drugs/2/drug-63989/escitalopram-oxalate-oral/details

Escitalopram is used to treat depression and anxiety. It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. Escitalopram belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRI).

https://www.hepmag.com/article/antidepressants-liver-25000-1355103308

A group of French researchers has argued that antidepressant medications, which all carry a risk of liver damage, are more toxic to the liver than past research has suggested, Medscape reports. Drugs whose risks are apparently lower include citalopram, escitalopram, paroxetine and fluvoxamine.